α-bromo acetophenone
2-Bromoacetophenone
CAS: 70-11-1
Molecular Formula: C8H7BrO
α-bromo acetophenone - Names and Identifiers
| Name | 2-Bromoacetophenone |
| Synonyms | Phenacyl bromide Bromoacetylbenzene 2-Bromoacetophenone w-Bromoacetophenone α-bromo acetophenone 2-Bromo acetophenone 1-(Bromoacetyl)benzene alpha-Bromoacetophenone roxylamine hydrochloride 2-Bromo-1-phenylethanone ω-Bromoacetophenone, Phenacyl bromide 2-Bromoacetophenone, 2-Bromo-1-phenylethan-1-one 2-Bromoacetophenone,ω-Bromoacetophenone, Phenacyl bromide |
| CAS | 70-11-1 |
| EINECS | 200-724-9 |
| InChI | InChI=1/C8H7BrO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2 |
| InChIKey | LIGACIXOYTUXAW-UHFFFAOYSA-N |
α-bromo acetophenone - Physico-chemical Properties
| Molecular Formula | C8H7BrO |
| Molar Mass | 199.04 |
| Density | 1.476 |
| Melting Point | 48-51 °C (lit.) |
| Boling Point | 135 °C/18 mmHg (lit.) |
| Flash Point | >230°F |
| Water Solubility | PRACTICALLY INSOLUBLE |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.0184mmHg at 25°C |
| Appearance | Crystals or Powder |
| Color | White to dark green-brown |
| Merck | 14,1402 |
| BRN | 606474 |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong bases, strong oxidizing agents. Combustible. |
| Refractive Index | 1.5700 (estimate) |
| Physical and Chemical Properties | Melting Point: 48 - 51 ℃ Boiling Point: 135 at 18mm Hg |
| Use | Used as a pharmaceutical Intermediate |
α-bromo acetophenone - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R34 - Causes burns R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2645 6.1/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-19 |
| TSCA | Yes |
| HS Code | 29143990 |
| Hazard Note | Corrosive |
| Hazard Class | 6.1 |
| Packing Group | II |
α-bromo acetophenone - Nature
Open Data Verified Data
white crystals. Melting Point 51 °c. Boiling point of 135 deg C (2. 40kPa). Refractive index (15 °c). Insoluble in water, soluble in ethanol, ether, chloroform and benzene. With the formation of high manganese acid benzoic acid.
Last Update：2025-06-10 22:55:16
α-bromo acetophenone - Preparation Method
Open Data Verified Data
obtained by bromination of acetophenone, in addition, acetophenone and bromine in the presence of aluminum oxide can also be obtained, the yield of 94%.
Last Update：2022-01-01 10:42:43
α-bromo acetophenone - Application
Open Data Verified Data
This product is a raw material for organic synthesis, used in the pharmaceutical industry for the preparation of hemostatic speed, etc., and thiourea can be used to synthesize a-amino -4-phenyl thiazole.
Last Update：2025-08-19 16:24:40
α-bromo acetophenone - Safety
Open Data Verified Data
- This product is toxic, with strong tear. It can burn when exposed to an open flame and emit a large amount of tear vapor when exposed to high heat.
- The glass bottle outer wooden box liner bedding or iron drum packaging. Store in a cool, ventilated room. Keep away from fire and heat source. With oxidant, edible raw materials Isolation storage and transportation. Light load and light discharge during handling to prevent damage to the container.
Last Update：2025-06-10 22:55:16
α-bromo acetophenone - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| purpose | This product is a raw material for organic synthesis and an intermediate for medicine and dye. In the pharmaceutical industry for the preparation of hemostatic speed, etc., and thiourea can be synthesized alpha-amino -4-phenyl thiazole. used as pharmaceutical intermediates organic synthesis raw materials, pharmaceutical industry used in the preparation of hemostatic speed, synthesis of α-amino -4-phenyl thiazole by interaction with thiourea |
| production method | is obtained by bromination of acetophenone. Add water and benzene to the reaction pan, stir, quickly add bromine at 25 ℃, slowly raise the temperature to 55-60 ℃, react for 10-20min, add ice water, cool to 0-5 ℃, spin filter, the filter cake was washed with ice water and spin dried to obtain bromoacetophenone. The yield was 92%. In the course of the above reaction, the reaction pot can make a loud noise. It is also possible to react acetophenone Dropwise with bromine in an ether solvent and add anhydrous aluminum trichloride to the reaction solution. The crude product was obtained in 88-96% yield. In addition, acetophenone and bromine in the presence of aluminum oxide can also be obtained, the yield of 94%. |
| category | toxic substances |
| flammability hazard characteristics | open flame flammable; Thermal decomposition of toxic bromide gas |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Storage and transportation are separated from oxidant and food raw materials |
| fire extinguishing agent | carbon dioxide, sand, foam |
Last Update：2024-04-09 02:00:10
Supplier List
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 2-Bromoacetophenone Visit Supplier Webpage Request for quotationCAS: 70-11-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-Bromoacetophenone Visit Supplier Webpage Request for quotationCAS: 70-11-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Bromoacetophenone Visit Supplier Webpage Request for quotationCAS: 70-11-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 2-Bromoacetophenone Request for quotationCAS: 70-11-1
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 2-Bromoacetophenone Visit Supplier Webpage Request for quotationCAS: 70-11-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-Bromoacetophenone Visit Supplier Webpage Request for quotationCAS: 70-11-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Bromoacetophenone Visit Supplier Webpage Request for quotationCAS: 70-11-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History